HitPredict

Interactor 1: GLE2 (P40066)
mRNA export factor GLE2 (Nuclear pore protein GLE2) (Nucleoporin GLE2) (poly(A) RNA export protein RAE1)
Gene: GLE2

Interactor 2: GCN5 (Q03330)
Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-)
Gene: GCN5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Acetyltransf_1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Sc			1 439
+	Hs
		943875 RAE1L_HUMAN (1-365): 8.11e-95: 288: 40.27		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Mm
		1207958 RAE1L_MOUSE (16-365): 1.23e-92: 283: 40.34		KAT2A_MOUSE (14-430): 1.8e-168: 495: 37.97
+	Hs
		903408 WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Mm
		903679 WDR5_MOUSE (2-67): 7.82e-10: 61.6: 10.29		KAT2A_MOUSE (14-430): 1.8e-168: 495: 37.97
+	Dm
		1358857 WDS_DROME (2-68): 6.34e-11: 65.1: 10.15		Q9VTZ1_DROME (42-432): 3.07e-148: 443: 38.56
+	Hs
		211163 BUB3_HUMAN (26-363): 4.13e-92: 280: 33.63		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		211087 BUB3_HUMAN (26-363): 4.13e-92: 280: 33.63		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		244941 WDR55_HUMAN (10-300): 1.57e-66: 216: 22.91		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		170444 SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55		TIF1A_HUMAN (225-438): 1.14e-49: 183: 22.83
+	Hs
		1346965 NLE1_HUMAN (214-363): 1.04e-26: 112: 11.92		BAZ2A_HUMAN (234-437): 2.83e-41: 159: 21.40
+	Hs
		244901 TBL1R_HUMAN (162-364): 2.4e-31: 125: 13.30		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		1346964 NLE1_HUMAN (214-363): 1.04e-26: 112: 11.92		BAZ2B_HUMAN (228-435): 1.92e-39: 153: 25.84
+	Hs
		1288369 SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55		BAZ2A_HUMAN (234-437): 2.83e-41: 159: 21.40
+	Hs
		1288368 SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55		BAZ2B_HUMAN (228-435): 1.92e-39: 153: 25.84
+	Hs
		244767 SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		236212 PRP17_HUMAN (157-343): 2.49e-16: 82.2: 10.31		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		998787 SMU1_HUMAN (70-234): 2.41e-11: 66.7: 18.33		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		903172 WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		244523 SMU1_HUMAN (70-234): 2.41e-11: 66.7: 18.33		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53
+	Hs
		244210 WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53