HitPredict

Interactor 1: LSM5 (P40089)
U6 snRNA-associated Sm-like protein LSm5
Gene: LSM5

Interactor 2: RUXG (P40204)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SMX2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	16554755
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:0071001 - U4/U6 snRNP
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 93 Sc			1 77
+	Sc
		768230 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM1_YEAST (2-75): 6.38e-23: 87.2: 25.97
+	Sc
		768241 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM7_YEAST (3-76): 9.05e-21: 80.3: 36.15
+	Hs
		1356295 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM7_HUMAN (3-77): 2.39e-25: 91.5: 35.80
+	Mm
		912782 LSM5_MOUSE (2-86): 8.78e-35: 115: 49.41		LSM7_MOUSE (3-77): 4.41e-25: 91.1: 37.04
+	Hs
		167727 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM1_HUMAN (1-75): 5.67e-22: 83.8: 31.58
+	Dm
		1368677 Q9VRT7_DROME (2-86): 6.04e-34: 113: 43.53		Q9VJI7_DROME (3-77): 4.39e-22: 83.4: 32.93
+	Dm
		1373283 Q9VRT7_DROME (2-86): 6.04e-34: 113: 43.53		Q9W2K2_DROME (1-76): 4.17e-21: 81.8: 28.57
+	Ce
		186307 O18694_CAEEL (2-86): 6.45e-33: 111: 42.35		Q23543_CAEEL (3-77): 3.39e-22: 83.8: 34.57
+	Sp
		194998 LSM5_SCHPO (5-86): 9.71e-33: 110: 46.34		LSM7_SCHPO (3-76): 1.02e-21: 82.6: 31.65
+	Hs
		321443 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM8_HUMAN (4-75): 7.23e-20: 77.6: 25.68
+	Sc
		768220 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM5_YEAST (7-73): 3.89e-09: 50.3: 26.39
+	Sc
		768245 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM3_YEAST (1-72): 8.95e-09: 49.1: 25.97
+	Hs
		928048 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		RSMN_HUMAN (7-71): 7.61e-09: 51.8: 19.18