HitPredict

Interactor 1: LSM5 (P40089)
U6 snRNA-associated Sm-like protein LSm5
Gene: LSM5

Interactor 2: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.984

Property	Details
Experiments	10900456, 10428970, 10747033, 11805826, 16429126, 17513695, 18719252, 18719247, 19111170, 37968396, 22450758, 10761922, 16554755, 14759368, 23267104
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification, biochemical, miniaturized immunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 93 Sc			1 172
+	Sc
		768241 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97
+	Hs
		167727 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22
+	Dm
		1373283 Q9VRT7_DROME (2-86): 6.04e-34: 113: 43.53		Q9W2K2_DROME (36-165): 9.12e-32: 112: 40.00
+	Sc
		768232 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM8_YEAST (43-150): 4.47e-21: 84.7: 18.52
+	Sc
		766910 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		RSMB_YEAST (35-153): 5.78e-20: 84: 21.32
+	Hs
		321443 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98
+	Sc
		768245 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		LSM3_YEAST (46-120): 1.16e-19: 80.2: 29.87
+	Sc
		768222 LSM5_YEAST (1-93): 3.69e-43: 137: 100.00		RUXG_YEAST (40-117): 4.06e-19: 78.6: 25.32
+	Sp
		194998 LSM5_SCHPO (5-86): 9.71e-33: 110: 46.34		LSM7_SCHPO (11-120): 3.83e-29: 105: 23.21
+	Hs
		928048 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24
+	Hs
		539203 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24
+	Hs
		1356295 LSM5_HUMAN (2-86): 8.78e-35: 115: 49.41		LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34
+	Mm
		912782 LSM5_MOUSE (2-86): 8.78e-35: 115: 49.41		LSM7_MOUSE (27-117): 2.08e-22: 87.8: 22.34
+	Dm
		1368677 Q9VRT7_DROME (2-86): 6.04e-34: 113: 43.53		Q9VJI7_DROME (27-119): 5.96e-20: 81.7: 21.65
+	Ce
		186307 O18694_CAEEL (2-86): 6.45e-33: 111: 42.35		Q23543_CAEEL (45-117): 5.72e-20: 81.7: 27.63