HitPredict

Interactor 1: NCB1 (P40096)
Negative cofactor 2 complex subunit alpha (NC2 complex subunit alpha) (Transcription repressor BUR6)
Gene: BUR6

Interactor 2: NCB2 (Q92317)
Negative cofactor 2 complex subunit beta (NC2 complex subunit beta) (Transcriptional repressor YDR1)
Gene: NCB2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 10655498, 11283351, 18048413, 18703679, 16554755, 18467557, 18719252, 37968396, 9096360
Identification Methods two hybrid, two hybrid pooling approach, affinity chromatography technology, protein complementation assay, ion exchange chromatography, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 142
Sc

1 146
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Last updated: 15 Jul 2024