HitPredict

Interactor 1: RUXG (P40204)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SMX2

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	11805826, 37968396, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000245 - spliceosomal complex assembly GO:0000398 - mRNA splicing, via spliceosome GO:0071004 - U2-type prespliceosome GO:0071011 - precatalytic spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 77 Sc			1 687
+	Sc
		865990 LSM7_YEAST (3-76): 9.05e-21: 80.3: 36.15		CLF1_YEAST (1-687): 7.93e-126: 390: 100.00
+	Hs
		912106 RUXG_HUMAN (5-77): 7.48e-27: 94.6: 53.43		CRNL1_HUMAN (5-685): 4.45e-115: 367: 36.61
+	Hs
		68456 RUXGL_HUMAN (5-77): 8.44e-26: 91.9: 49.32		CRNL1_HUMAN (5-685): 4.45e-115: 367: 36.61
+	Sc
		770333 RUXG_YEAST (1-77): 1.83e-26: 93.8: 100.00		SYF1_YEAST (54-674): 1.42e-57: 211: 11.97
+	Hs
		912115 RUXG_HUMAN (5-77): 7.48e-27: 94.6: 53.43		SYF1_HUMAN (2-495): 4.59e-26: 116: 14.67
+	Hs
		68460 RUXGL_HUMAN (5-77): 8.44e-26: 91.9: 49.32		SYF1_HUMAN (2-495): 4.59e-26: 116: 14.67
+	Sp
		252597 RUXG_SCHPO (2-77): 3.36e-20: 77.6: 46.05		PRP1_SCHPO (1-392): 2.83e-20: 98.1: 13.22
+	Hs
		912043 RUXG_HUMAN (5-77): 7.48e-27: 94.6: 53.43		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Hs
		68420 RUXGL_HUMAN (5-77): 8.44e-26: 91.9: 49.32		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Hs
		1063305 LSM7_HUMAN (3-77): 2.39e-25: 91.5: 35.80		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Hs
		300100 RUXG_HUMAN (5-77): 7.48e-27: 94.6: 53.43		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89
+	Sc
		586412 RUXG_YEAST (1-77): 1.83e-26: 93.8: 100.00		PRP6_YEAST (28-198): 6.71e-10: 64.6: 13.30
+	Hs
		68390 RUXGL_HUMAN (5-77): 8.44e-26: 91.9: 49.32		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89
+	Hs
		300284 LSM7_HUMAN (3-77): 2.39e-25: 91.5: 35.80		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89
+	Sp
		1013603 RSMB_SCHPO (3-72): 2.29e-09: 51.8: 20.51		PRP1_SCHPO (1-392): 2.83e-20: 98.1: 13.22
+	Hs
		167651 LSM1_HUMAN (1-75): 5.67e-22: 83.8: 31.58		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89
+	Hs
		321401 LSM8_HUMAN (4-75): 7.23e-20: 77.6: 25.68		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Sc
		586429 LSM7_YEAST (3-76): 9.05e-21: 80.3: 36.15		PRP6_YEAST (28-198): 6.71e-10: 64.6: 13.30
+	Hs
		927951 RSMN_HUMAN (7-71): 7.61e-09: 51.8: 19.18		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Hs
		300110 RSMN_HUMAN (7-71): 7.61e-09: 51.8: 19.18		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89