HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 531 Hs			1 768
+	Hs
		1042381 TCPH_HUMAN (2-530): 0: 576: 27.93		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		826653 TCPG_HUMAN (3-528): 0: 559: 27.96		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		821202 TCPE_HUMAN (3-528): 0: 548: 30.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042171 TCPW_HUMAN (1-530): 0: 542: 85.85		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		821203 TCPE_HUMAN (3-528): 0: 548: 30.47		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Sp
		251317 TCPG_SCHPO (2-527): 0: 555: 28.76		CUL3_SCHPO (11-768): 0: 648: 37.04