HitPredict

Interactor 1: OPRM (P35372)
Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
Gene: OPRM1

Interactor 2: WLS (Q5T9L3)
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
Gene: WLS

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	23840749, 28298427, 31286866, 20214800
Identification Methods	two hybrid, pull down, affinity chromatography technology, ubiquitin reconstruction, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 541
+	Mm
		844165 OPRM_MOUSE (1-400): 1.12e-104: 316: 94.00		WLS_MOUSE (1-541): 0: 812: 96.12
+	Rn
		753860 OPRM_RAT (1-400): 8.65e-105: 316: 94.00		WLS_RAT (1-541): 0: 808: 95.75
+	Hs
		832385 OPRK_HUMAN (13-374): 3.42e-84: 263: 56.83		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		832368 OPRD_HUMAN (22-383): 4.08e-83: 260: 60.33		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		835485 CCR2_HUMAN (31-365): 6.94e-71: 228: 23.75		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		669079 FPR2_HUMAN (71-346): 4.52e-36: 136: 32.08		TM181_HUMAN (96-507): 8.55e-123: 370: 19.76