HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 427
+	Hs
		1265890 TCPH_HUMAN (2-530): 0: 576: 27.93		DDB2_HUMAN (1-427): 1.81e-95: 294: 100.00
+	Hs
		1306687 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		1202777 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (142-427): 6.44e-67: 218: 14.53
+	Hs
		770916 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (142-427): 6.44e-67: 218: 14.53
+	Hs
		770968 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (5-311): 1.3e-61: 213: 12.14
+	Hs
		1028020 TCPH_HUMAN (2-530): 0: 576: 27.93		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		770812 TCPZ_HUMAN (1-531): 0: 573: 100.00		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		903467 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		770771 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		1240450 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (6-228): 3.78e-46: 165: 11.66
+	Hs
		770932 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (6-228): 3.78e-46: 165: 11.66
+	Hs
		1306704 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (279-427): 4.77e-30: 123: 16.77
+	Sc
		761113 TCPZ_YEAST (3-530): 0: 579: 56.75		CMR1_YEAST (98-427): 4.9e-26: 112: 17.49
+	Hs
		770974 TCPZ_HUMAN (1-531): 0: 573: 100.00		SNR40_HUMAN (272-427): 1.08e-24: 106: 12.58
+	Sc
		761112 TCPZ_YEAST (3-530): 0: 579: 56.75		PRP46_YEAST (114-427): 9.01e-19: 89.8: 16.36
+	Hs
		1306645 TCPH_HUMAN (2-530): 0: 576: 27.93		TBL1Y_HUMAN (277-427): 1.56e-18: 89.5: 11.88
+	Hs
		921697 TCPH_HUMAN (2-530): 0: 576: 27.93		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		770778 TCPZ_HUMAN (1-531): 0: 573: 100.00		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		197078 TCPH_HUMAN (2-530): 0: 576: 27.93		PRP4_HUMAN (273-421): 2.01e-16: 83.2: 12.67
+	Hs
		196964 TCPZ_HUMAN (1-531): 0: 573: 100.00		PRP4_HUMAN (273-421): 2.01e-16: 83.2: 12.67