Protein: MDHM
Malate dehydrogenase, mitochondrial (EC 1.1.1.37)

Gene: MDHM, Mdh2
Organism: Mus musculus
Interactions: 80
UniProt ID: P08249

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006094 - gluconeogenesis
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

469578

MDHM
Malate dehydrogenase, mitochondrial

3

14

High-throughput

0.827

High

426374

AATM
Aspartate aminotransferase, mitochondrial

3

3

High-throughput

0.640

High

469586

CACP
Carnitine O-acetyltransferase

3

2

High-throughput

0.640

High

469598

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

3

6

High-throughput

0.640

High

469625

ACON
Aconitate hydratase, mitochondrial

3

4

High-throughput

0.640

High

469591

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

2

6

High-throughput

0.584

High

469612

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

2

8

High-throughput

0.584

High

469630

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

2

2

High-throughput

0.584

High

469634

CISY
Citrate synthase, mitochondrial

2

7

Small-scale

0.584

High

469642

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

2

2

High-throughput

0.584

High

469644

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

2

2

High-throughput

0.584

High

469648

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

2

3

High-throughput

0.584

High

469599

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

5

High-throughput

0.536

High

108399

G3X9H5
Huntingtin

2

6

Small-scale

0.533

High

148154

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

204864

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

8

High-throughput

0.479

High

469580

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.479

High

469581

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

6

High-throughput

0.479

High

469583

HSPA9
Stress-70 protein, mitochondrial

1

10

High-throughput

0.479

High

469584

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

469585

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

469588

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

469590

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

3

High-throughput

0.479

High

469593

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

469595

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

2

High-throughput

0.479

High

469596

FUMH
Fumarate hydratase, mitochondrial

1

3

High-throughput

0.479

High

469604

ABCD2
ATP-binding cassette sub-family D member 2

1

1

High-throughput

0.479

High

469605

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

469607

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.479

High

469608

Q80X68
Citrate synthase

1

7

High-throughput

0.479

High

469609

MIRO1
Mitochondrial Rho GTPase 1

1

3

High-throughput

0.479

High

469611

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

1

High-throughput

0.479

High

469613

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

3

High-throughput

0.479

High

469614

Q8C1W8
NAD(P) transhydrogenase, mitochondrial

1

1

High-throughput

0.479

High

469615

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

469617

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

5

High-throughput

0.479

High

469618

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

5

High-throughput

0.479

High

469620

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

3

High-throughput

0.479

High

469622

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

2

High-throughput

0.479

High

469623

S25A3
Solute carrier family 25 member 3

1

3

High-throughput

0.479

High

469624

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

1

High-throughput

0.479

High

469626

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

3

High-throughput

0.479

High

469627

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

469629

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

2

High-throughput

0.479

High

469633

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

6

High-throughput

0.479

High

469636

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

1

High-throughput

0.479

High

469639

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.479

High

469640

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

7

High-throughput

0.479

High

469641

Q9D881
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.479

High

469643

ETFB
Electron transfer flavoprotein subunit beta

1

3

High-throughput

0.479

High

469645

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

469649

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

4

High-throughput

0.479

High

397822

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.458

High

469579

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

469587

ADT1
ADP/ATP translocase 1

1

0

High-throughput

0.458

High

469621

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.458

High

469631

ACO13
Acyl-coenzyme A thioesterase 13

1

0

High-throughput

0.458

High

469632

RCC1L
RCC1-like G exchanging factor-like protein

1

0

High-throughput

0.458

High

469635

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.458

High

469637

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

469638

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

469646

ITA2B
Integrin alpha-IIb

1

5

High-throughput

0.457

High

469594

1433F
14-3-3 protein eta

1

5

High-throughput

0.445

High

469647

B9D1
B9 domain-containing protein 1

1

1

Small-scale

0.445

High

398028

CFAD
Complement factor D

1

1

High-throughput

0.437

High

469589

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.437

High

469597

MYH6
Myosin-6

1

3

High-throughput

0.437

High

469601

Q3UJF1
Histone deacetylase

1

9

High-throughput

0.437

High

469602

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

2

High-throughput

0.437

High

469603

CLU
Clustered mitochondria protein homolog

1

1

High-throughput

0.437

High

469606

NEB2
Neurabin-2

1

6

High-throughput

0.437

High

469610

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.437

High

469616

MT21E
Protein-lysine methyltransferase METTL21E

1

7

High-throughput

0.437

High

469619

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

469628

FBX32
F-box only protein 32

1

1

High-throughput

0.437

High

469650

HDAC5
Histone deacetylase 5

1

9

High-throughput

0.407

High

469582

SSR3
Somatostatin receptor type 3

1

0

High-throughput

0.249

Low

469592

WFS1
Wolframin

1

0

High-throughput

0.249

Low

469600

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025