HitPredict

Interactor 1: PSA2 (P40301)
Proteasome subunit alpha type-2 (PROS-Dm25) (Proteasome 25 kDa subunit)
Gene: Prosalpha2

Interactor 2: Q8T8V8 (Q8T8V8)
Proteasome subunit beta
Gene: Prosbeta5R1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Dm			1 315
+	Hs
		637629 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96
+	Dm
		1178944 PSA5_DROME (1-233): 1.55e-97: 286: 30.71		Q7K148_DROME (1-280): 2.97e-98: 292: 59.01
+	Hs
		656152 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18
+	Sp
		293714 PSA2_SCHPO (3-233): 1.96e-107: 311: 58.20		PSA3_SCHPO (44-272): 4.02e-76: 235: 15.64
+	Ce
		1099874 PSA2_CAEEL (4-233): 3.6e-99: 289: 60.35		PBS5_CAEEL (16-271): 4.13e-82: 251: 37.78
+	Hs
		656149 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA5_HUMAN (34-270): 9.93e-82: 249: 16.53
+	Sp
		675393 PSA5_SCHPO (1-231): 3.4e-100: 293: 32.77		PSB5_SCHPO (66-285): 2.64e-77: 239: 51.82
+	Mt
		191406 PSA_METTH (1-233): 1.2e-102: 299: 36.17		PSB_METTH (65-268): 1.65e-75: 232: 29.27
+	Hs
		637631 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA2_HUMAN (38-271): 1e-78: 241: 15.06
+	Hs
		637624 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA2_HUMAN (38-271): 1e-78: 241: 15.06
+	Mm
		1154361 PSA_METMP (4-233): 8.01e-99: 290: 34.05		PSB_METMP (58-269): 7.18e-75: 230: 28.51
+	Af
		191426 PSA_ARCFU (5-231): 5.1e-97: 285: 40.18		PSB_ARCFU (70-272): 4.89e-76: 233: 27.94
+	Hs
		656151 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSB6_HUMAN (67-254): 6.05e-74: 229: 30.16
+	Hs
		656296 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSB7_HUMAN (31-263): 5.56e-73: 228: 24.46
+	Dm
		1278650 PSA5_DROME (1-233): 1.55e-97: 286: 30.71		Q9VUJ1_DROME (48-265): 1.64e-73: 229: 26.61
+	Hs
		656164 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSB10_HUMAN (47-260): 2.71e-71: 223: 28.24
+	Dm
		47610 PSA5_DROME (1-233): 1.55e-97: 286: 30.71		A0AQH0_DROME (70-254): 6.35e-70: 218: 28.50
+	Ph
		223381 PSA_PYRHO (4-231): 1.88e-101: 296: 41.74		PSB1_PYRHO (66-254): 3.33e-27: 107: 33.16
+	Hs
		656090 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSB9_HUMAN (71-254): 6.24e-19: 85.5: 30.81
+	Hs
		637630 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSB9_HUMAN (71-254): 6.24e-19: 85.5: 30.81