Interactor 1: HES1 (P35428)
Transcription factor HES-1 (Hairy and enhancer of split 1)
Gene: HES1

Interactor 2: IKBA (Q9Z1E3)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha)
Gene: Nfkbia

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15536134
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007219 - Notch signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 282
Mm

1 314
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025