Interactor 1: SCN4A (P35499)
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
Gene: SCN4A
Interactor 2: SCN1B (Q07699)
Sodium channel regulatory subunit beta-1
Gene: SCN1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.666 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30190309 |
| Identification Methods | 3D electron microscopy, molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ion_trans~V-set |
| Common GO terms | GO:0001518 - voltage-gated sodium channel complex GO:0005886 - plasma membrane GO:0035725 - sodium ion transmembrane transport GO:0086002 - cardiac muscle cell action potential involved in contraction |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
