Interactor 1: SCN7A (Q01118)
Sodium channel protein type 7 subunit alpha (Atypical sodium channel Nav2.1) (Nax channel) (Sodium channel protein type VII subunit alpha)
Gene: SCN7A
Interactor 2: SCN3B (Q9NY72)
Sodium channel regulatory subunit beta-3
Gene: SCN3B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.666 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35301303 |
| Identification Methods | 3D electron microscopy, molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ion_trans~V-set |
| Common GO terms | GO:0001518 - voltage-gated sodium channel complex GO:0005886 - plasma membrane GO:0035725 - sodium ion transmembrane transport GO:0044325 - transmembrane transporter binding GO:0086002 - cardiac muscle cell action potential involved in contraction |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
