Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.771

The method score is based on:

Property Details
Experiments 31253590, 12697815, 12048197, 17922844, 18187417, 15935760, 10449727, 25500545, 25661653, 26735018, 26751167, 27517496, 28514442, 28775317, 17353931, 10587522, 30890701, 24981860, 32328410, 33961781 and 26 others

more...

Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0030891 - VCB complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 213
Hs

1 118
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024