Interactor 1: VHL (P40338)
von Hippel-Lindau disease tumor suppressor (pVHL)
Gene: VHL
Interactor 2: EPAS1 (P97481)
Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha)
Gene: EPAS1
Species: Mus musculus
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20211142 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HIF-1~VHL |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001525 - angiogenesis GO:0001666 - response to hypoxia GO:0005634 - nucleus GO:0005737 - cytoplasm |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
