Protein: PAP2
Poly(A) RNA polymerase protein 2 (EC 2.7.7.19) (DNA polymerase kappa) (DNA polymerase sigma) (Topoisomerase 1-related protein TRF4)

Gene: PAP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 104
UniProt ID: P53632

Gene Ontology (top 5):
GO:0000292 - RNA fragment catabolic process
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

922191

AIR2
Protein AIR2

16

8

Small-scale

0.988

High

825623

AIR1
Protein AIR1

8

7

Small-scale

0.967

High

921598

NRD1
Protein NRD1

7

0

Small-scale

0.925

High

874226

TRF5
Poly(A) RNA polymerase protein 1

3

4

Small-scale

0.829

High

922186

YRA1
RNA annealing protein YRA1

2

5

Small-scale

0.776

High

403603

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

2

Small-scale

0.767

High

864485

MTR4
ATP-dependent RNA helicase DOB1

14

6

Small-scale

0.762

High

808767

NAB3
Nuclear polyadenylated RNA-binding protein 3

2

0

Small-scale

0.748

High

917439

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

3

Small-scale

0.650

High

518090

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.646

High

524711

HSP71
Heat shock protein SSA1

3

5

High-throughput

0.633

High

922184

NOP53
Ribosome biogenesis protein NOP53

2

2

Small-scale

0.619

High

676756

GBP2
Serine/arginine

1

2

Small-scale

0.618

High

741036

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

3

Small-scale

0.618

High

922172

NOP3
Serine/arginine

1

11

Small-scale

0.618

High

922181

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.618

High

922188

BBP
Branchpoint-bridging protein

1

1

Small-scale

0.618

High

922189

NOP56
Nucleolar protein 56

2

4

Small-scale

0.611

High

734708

IMB3
Importin subunit beta-3

2

1

High-throughput

0.601

High

645481

XRN1
5'-3' exoribonuclease 1

2

2

Small-scale

0.594

High

590212

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

2

3

Small-scale

0.576

High

754500

RT05
Small ribosomal subunit protein uS5m

2

2

High-throughput

0.567

High

642064

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

Small-scale

0.552

High

819384

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

670311

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.536

High

893136

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.536

High

893192

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.536

High

747748

SMC1
Structural maintenance of chromosomes protein 1

1

1

Small-scale

0.515

High

808597

SMC2
Structural maintenance of chromosomes protein 2

1

1

Small-scale

0.515

High

830052

HUL4
Probable E3 ubiquitin-protein ligase HUL4

1

3

Small-scale

0.515

High

922185

RRP6
Exosome complex exonuclease RRP6

1

4

Small-scale

0.501

High

367083

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.500

High

386807

TBB
Tubulin beta chain

1

1

High-throughput

0.500

High

452944

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.500

High

486268

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.500

High

486499

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.500

High

510695

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.500

High

592403

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.500

High

597227

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.500

High

676220

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.500

High

676961

SRO9
RNA-binding protein SRO9

1

2

High-throughput

0.500

High

812980

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

2

High-throughput

0.500

High

865020

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.500

High

922171

ACT
Actin

1

1

High-throughput

0.500

High

922179

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

922183

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.500

High

672924

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.493

High

744393

ATC5
Phospholipid-transporting ATPase DNF1

1

0

High-throughput

0.493

High

738891

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.480

High

405121

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.479

High

408335

GAL1
Galactokinase

1

0

High-throughput

0.479

High

416464

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

453716

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.479

High

922170

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.479

High

922190

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.479

High

149883

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

382249

H4
Histone H4

1

1

High-throughput

0.479

High

383820

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

410257

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

433766

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

436086

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

455186

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

504338

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

512568

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

513137

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

585326

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

Small-scale

0.479

High

677505

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

689579

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

700266

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

2

Small-scale

0.479

High

707784

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

735529

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.479

High

738233

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

4

Small-scale

0.479

High

747498

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

792170

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

816527

SNU13
13 kDa ribonucleoprotein-associated protein

1

4

Small-scale

0.479

High

863119

RRP41
Exosome complex component SKI6

1

3

Small-scale

0.479

High

921187

THO2
THO complex subunit 2

1

2

Small-scale

0.479

High

922169

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

922173

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

922174

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.479

High

922175

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

2

Small-scale

0.479

High

922176

ARX1
Probable metalloprotease ARX1

1

1

Small-scale

0.479

High

922177

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

922178

RRP5
rRNA biogenesis protein RRP5

1

3

Small-scale

0.479

High

922180

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

922187

MAK21
Ribosome biogenesis protein MAK21

1

1

Small-scale

0.479

High

922192

NOP58
Nucleolar protein 58

1

4

Small-scale

0.479

High

442037

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

503164

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

514757

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

603090

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

751443

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.458

High

778460

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

802300

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

814353

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.458

High

874446

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

922166

MPP6
M-phase phosphoprotein 6 homolog

1

0

Small-scale

0.458

High

922167

CAF40
Protein CAF40

1

0

Small-scale

0.458

High

922182

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

Small-scale

0.458

High

527308

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

545750

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

670973

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

742087

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

922168

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High


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Last updated: 11Aug2025