Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: PHB1 (P67778)
Prohibitin 1 (B-cell receptor-associated protein 32) (BAP 32)
Gene: PHB1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.39 | 0.60 | 0.484 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15602769 |
| Identification Methods | tandem affinity purification, coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Homologous interactions | 4 |
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Last updated: 11Aug2025