HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1976 Hs			1 1863
+	Hs
		772651 MYH9_HUMAN (8-1930): 0: 1056: 78.89		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		799241 MYH14_HUMAN (27-1930): 0: 1013: 68.33		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		773270 MYH10_HUMAN (1-1976): 0: 1086: 100.00		TRIM6_HUMAN (10-377): 7.06e-68: 240: 13.54
+	Hs
		773006 MYH9_HUMAN (8-1930): 0: 1056: 78.89		TRIM6_HUMAN (10-377): 7.06e-68: 240: 13.54
+	Hs
		773269 MYH10_HUMAN (1-1976): 0: 1086: 100.00		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Hs
		773005 MYH9_HUMAN (8-1930): 0: 1056: 78.89		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Hs
		1277780 MYH14_HUMAN (27-1930): 0: 1013: 68.33		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Mm
		1169543 MYH9_MOUSE (8-1930): 0: 1055: 78.21		TRI72_MOUSE (18-91): 9.45e-12: 71.5: 30.26
+	Hs
		563033 MYH6_HUMAN (1241-1976): 7.15e-50: 198: 18.27		TRIM6_HUMAN (10-377): 7.06e-68: 240: 13.54
+	Hs
		556952 MYH7_HUMAN (723-1572): 2.21e-46: 186: 16.34		TRIM6_HUMAN (10-377): 7.06e-68: 240: 13.54