HitPredict

Interactor 1: COPB2 (P35606)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)
Gene: COPB2

Interactor 2: COPB (P53618)
Coatomer subunit beta (Beta-coat protein) (Beta-COP)
Gene: COPB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.940

The method score is based on:

Property	Details
Experiments	10921873, 8940050, 9751720, 35271311, 39358380, 14729954
Identification Methods	two hybrid, affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Adaptin_N~Coatomer_WDAD, Coatamer_beta_C~Coatomer_WDAD, Coatomer_WDAD~Coatomer_b_Cpla
Common GO terms	GO:0000139 - Golgi membrane GO:0005198 - structural molecule activity GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0006886 - intracellular protein transport and 4 others more... GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006891 - intra-Golgi vesicle-mediated transport GO:0030126 - COPI vesicle coat GO:0030133 - transport vesicle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	906
Hs

1	953

Service provided by Combinatics, Japan

Last updated: 11Aug2025