Interactor 1: NDC80 (P40460)
Kinetochore protein NDC80 (80 kDa spindle component protein) (Nuclear division cycle protein 80) (Two-hybrid interaction with DMC1 protein 3)
Gene: NDC80
Interactor 2: MPS1 (P54199)
Serine/threonine-protein kinase MPS1 (EC 2.7.12.2) (Monopolar spindle protein 1) (Regulatory cell proliferation kinase 1)
Gene: MPS1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.751 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17634282, 38776904, 34647959, 19300438, 38776902, 20368617, 20489023 |
| Identification Methods | two hybrid, unspecified method, pull down, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay |
| Interaction Type | direct interaction, physical association, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000776 - kinetochore GO:0005634 - nucleus GO:0007059 - chromosome segregation GO:0034501 - protein localization to kinetochore |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
