Protein: ADDG
Gamma-adducin (Adducin-like protein 70)

Gene: ADDG, ADD3
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q9UEY8

Gene Ontology (top 5):
GO:0000794 - condensed nuclear chromosome
GO:0005080 - protein kinase C binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005516 - calmodulin binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

774124

ADDA
Alpha-adducin

2

4

High-throughput

0.811

High

774176

ADDB
Beta-adducin

2

4

High-throughput

0.811

High

376056

RASK
GTPase KRas

5

20

High-throughput

0.702

High

1329230

ANR29
Ankyrin repeat domain-containing protein 29

4

8

High-throughput

0.630

High

736929

GBP2
Guanylate-binding protein 2

2

3

High-throughput

0.628

High

1437948

ELL3
RNA polymerase II elongation factor ELL3

2

4

High-throughput

0.611

High

1207291

FA78A
Protein FAM78A

3

1

High-throughput

0.599

High

243202

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

374258

RASN
GTPase NRas

2

20

High-throughput

0.584

High

540732

LAMP1
Lysosome-associated membrane glycoprotein 1

2

4

High-throughput

0.584

High

975294

ARF6
ADP-ribosylation factor 6

2

2

High-throughput

0.584

High

415916

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.541

High

720708

AGTR1
Type-1 angiotensin II receptor

1

2

High-throughput

0.541

High

770932

OPRM
Mu-type opioid receptor

1

3

High-throughput

0.541

High

530514

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

866854

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

920521

DAPK1
Death-associated protein kinase 1

1

8

High-throughput

0.536

High

993367

ACTG
Actin, cytoplasmic 2

1

6

High-throughput

0.536

High

1114559

CUL3
Cullin-3

1

6

High-throughput

0.536

High

1117697

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.536

High

1152282

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.536

High

1325461

SYNPO
Synaptopodin

1

2

High-throughput

0.536

High

1387288

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

1392689

MYO19
Unconventional myosin-XIX

1

4

High-throughput

0.536

High

1412774

FEM1A
Protein fem-1 homolog A

1

7

High-throughput

0.536

High

1414854

MELPH
Melanophilin

1

1

High-throughput

0.536

High

927594

ATX1
Ataxin-1

1

0

High-throughput

0.518

High

995870

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.515

High

838392

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.513

High

1252787

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.513

High

1459060

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.513

High

993792

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

1122917

SIM2
Single-minded homolog 2

1

1

High-throughput

0.494

High

926258

CRIS3
Cysteine-rich secretory protein 3

1

1

High-throughput

0.489

High

1259077

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.489

High

1352228

TBCK
TBC domain-containing protein kinase-like protein

1

4

High-throughput

0.489

High

1417726

HDAC8
Histone deacetylase 8

1

1

High-throughput

0.489

High

1459056

KLF15
Krueppel-like factor 15

1

1

High-throughput

0.489

High

126856

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

173504

XPO1
Exportin-1

1

4

High-throughput

0.479

High

189906

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

299418

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

327490

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.479

High

341160

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

374984

RASH
GTPase HRas

1

14

High-throughput

0.479

High

401652

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

414780

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

463819

LYN
Tyrosine-protein kinase Lyn

1

5

High-throughput

0.479

High

556397

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

562466

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.479

High

581356

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

583003

EZRI
Ezrin

1

5

High-throughput

0.479

High

601482

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

604258

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

710545

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.479

High

714492

PML
Protein PML

1

2

High-throughput

0.479

High

715825

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

731671

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

845843

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.479

High

862516

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

891344

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.479

High

891853

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

901085

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

902128

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

907613

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

910242

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

941852

ARL4C
ADP-ribosylation factor-like protein 4C

1

9

High-throughput

0.479

High

953157

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.479

High

953737

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

955720

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

956527

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

962599

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

962851

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

976635

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

978379

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988796

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1004230

CXAR
Coxsackievirus and adenovirus receptor

1

5

High-throughput

0.479

High

1015881

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1041348

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1145152

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.479

High

1146489

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

1151917

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1159892

OCLN
Occludin

1

4

High-throughput

0.479

High

1197739

MIDN
Midnolin

1

1

High-throughput

0.479

High

1233551

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1255954

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1271036

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1289685

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1323031

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.479

High

1326521

ARL14
ADP-ribosylation factor-like protein 14

1

4

High-throughput

0.479

High

1360839

ASB11
Ankyrin repeat and SOCS box protein 11

1

6

High-throughput

0.479

High

1366904

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1400345

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1402332

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

1428997

WWTR1
WW domain-containing transcription regulator protein 1

1

4

High-throughput

0.479

High

1432992

DNJC5
DnaJ homolog subfamily C member 5

1

7

High-throughput

0.479

High

1433561

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1434146

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1438222

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1439414

E41LA
Band 4.1-like protein 4A

1

4

High-throughput

0.479

High

1447390

ANLN
Anillin

1

2

High-throughput

0.479

High

1459054

DNJ5B
DnaJ homolog subfamily C member 5B

1

7

High-throughput

0.479

High

1459055

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1459057

ALK
ALK tyrosine kinase receptor

1

6

High-throughput

0.479

High

1459058

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

154509

CLD4
Claudin-4

1

0

Small-scale

0.458

High

226248

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

831590

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

880732

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

1024909

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1324101

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

844052

HD
Huntingtin

1

3

High-throughput

0.457

High

255263

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

430465

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

756395

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.445

High

942941

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.445

High

1235004

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

1292300

S2611
Sodium-independent sulfate anion transporter

1

1

High-throughput

0.445

High

1459059

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

106795

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

140020

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

589949

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696772

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

769424

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

991952

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.437

High

1276912

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1381991

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

1404820

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.437

High

1452123

ARL15
ADP-ribosylation factor-like protein 15

1

7

High-throughput

0.437

High

906365

GPC3
Glypican-3

1

0

High-throughput

0.426

High

1155110

UT2
Urea transporter 2

1

0

High-throughput

0.426

High

139424

VMA5A
von Willebrand factor A domain-containing protein 5A

2

0

High-throughput

0.328

High

416046

CP1A1
Cytochrome P450 1A1

2

0

High-throughput

0.318

High

485956

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.279

Low

1390566

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

1399669

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

0

High-throughput

0.279

Low

1459061

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

1289328

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1293187

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1328455

S2541
Mitochondrial carrier protein SCaMC-3L

1

0

High-throughput

0.249

Low

1459062

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025