Protein: SYNJ2
Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)

Gene: SYNJ2
Organism: Homo sapiens
Interactions: 46
UniProt ID: O15056

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

176275

SH3K1
SH3 domain-containing kinase-binding protein 1

7

20

Small-scale

0.742

High

176257

1433G
14-3-3 protein gamma

4

16

High-throughput

0.699

High

176260

RAC1
Ras-related C3 botulinum toxin substrate 1

3

6

Small-scale

0.678

High

176262

1433F
14-3-3 protein eta

3

16

High-throughput

0.667

High

176259

GRB2
Growth factor receptor-bound protein 2

3

20

High-throughput

0.654

High

176250

1433B
14-3-3 protein beta/alpha

3

16

High-throughput

0.650

High

176258

1433E
14-3-3 protein epsilon

2

2

High-throughput

0.611

High

176251

1433S
14-3-3 protein sigma

2

16

High-throughput

0.601

High

176277

ITSN2
Intersectin-2

2

9

Small-scale

0.595

High

176247

1433T
14-3-3 protein theta

1

16

High-throughput

0.554

High

176268

H32
Histone H3.2

2

1

High-throughput

0.533

High

176261

PRKDC
DNA-dependent protein kinase catalytic subunit

1

2

High-throughput

0.515

High

176274

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

176255

SYJ2B
Synaptojanin-2-binding protein

1

4

Small-scale

0.481

High

176266

ITSN1
Intersectin-1

1

15

High-throughput

0.481

High

176238

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

176239

ABL1
Tyrosine-protein kinase ABL1

1

16

High-throughput

0.479

High

176240

FYN
Tyrosine-protein kinase Fyn

1

16

High-throughput

0.479

High

176241

PROF1
Profilin-1

1

4

High-throughput

0.479

High

176242

VIME
Vimentin

1

10

High-throughput

0.479

High

176243

CLCA
Clathrin light chain A

1

4

High-throughput

0.479

High

176244

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

176246

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

176248

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

5

High-throughput

0.479

High

176249

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.479

High

176253

VASP
Vasodilator-stimulated phosphoprotein

1

3

High-throughput

0.479

High

176256

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

176263

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

176264

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.479

High

176265

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

176269

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.479

High

176271

GOLM1
Golgi membrane protein 1

1

1

High-throughput

0.479

High

176272

CIP2A
Protein CIP2A

1

1

High-throughput

0.479

High

176273

BICD2
Protein bicaudal D homolog 2

1

8

High-throughput

0.479

High

176279

ANC2
Anaphase-promoting complex subunit 2

1

3

High-throughput

0.479

High

176280

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

176276

CK054
Ester hydrolase C11orf54

1

0

High-throughput

0.458

High

138415

BIN1
Myc box-dependent-interacting protein 1

1

10

High-throughput

0.457

High

176281

CD2AP
CD2-associated protein

1

20

High-throughput

0.457

High

176278

PARP2
Poly [ADP-ribose] polymerase 2

1

1

Small-scale

0.445

High

176282

SNX9
Sorting nexin-9

1

5

High-throughput

0.445

High

176245

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

176252

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

176254

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.437

High

176267

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.407

High

176270

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025