HitPredict

Interactor 1: AIR1 (P40507)
Protein AIR1 (Arginine methyltransferase-interacting RING finger protein 1)
Gene: AIR1

Interactor 2: NOP3 (Q01560)
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)
Gene: NPL3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	11805837, 10896665, 32561742
Identification Methods	anti tag coimmunoprecipitation, pull down, two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 360 Sc			1 414
+	Sc
		965517 AIR2_YEAST (12-357): 4.82e-83: 258: 45.07		NOP3_YEAST (1-414): 6.5e-65: 215: 100.00
+	Sc
		376814 AIR1_YEAST (1-360): 7.34e-117: 344: 100.00		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Sc
		376983 AIR2_YEAST (12-357): 4.82e-83: 258: 45.07		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Sc
		865289 GIS2_YEAST (132-234): 4.36e-12: 65.5: 19.64		NOP3_YEAST (1-414): 6.5e-65: 215: 100.00
+	Hs
		1029124 ZCHC3_HUMAN (50-144): 1.71e-23: 102: 26.04		SRSF6_HUMAN (126-274): 1.55e-44: 159: 25.82
+	Hs
		992957 ZCHC3_HUMAN (50-144): 1.71e-23: 102: 26.04		SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40
+	Hs
		1028841 ZCHC3_HUMAN (50-144): 1.71e-23: 102: 26.04		SRSF5_HUMAN (122-272): 1.04e-33: 128: 25.00
+	Hs
		914744 CNBP_HUMAN (132-244): 2.02e-12: 67: 14.62		SRSF6_HUMAN (126-274): 1.55e-44: 159: 25.82
+	Hs
		1232768 ZCHC7_HUMAN (54-360): 2.72e-45: 164: 19.81		RBM4B_HUMAN (199-278): 3.99e-09: 59.9: 16.25
+	Hs
		1020336 ZCHC3_HUMAN (50-144): 1.71e-23: 102: 26.04		ELAV2_HUMAN (106-182): 7.18e-13: 71.4: 17.65
+	Hs
		516714 ZCHC3_HUMAN (50-144): 1.71e-23: 102: 26.04		PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15
+	Sc
		633976 GIS2_YEAST (132-234): 4.36e-12: 65.5: 19.64		GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86
+	Sc
		376882 GIS2_YEAST (132-234): 4.36e-12: 65.5: 19.64		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Hs
		914823 CNBP_HUMAN (132-244): 2.02e-12: 67: 14.62		PABP3_HUMAN (190-285): 3.3e-10: 63.7: 13.13