HitPredict

Interactor 1: UBP8 (P40818)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: USP8

Interactor 2: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	26507658
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1118 Hs			1 129
+	Hs
		271104 UBP2_HUMAN (527-1111): 7.7e-120: 384: 29.62		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		271018 UBP2_HUMAN (527-1111): 7.7e-120: 384: 29.62		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391991 UBP3_HUMAN (628-1113): 3.22e-115: 369: 25.05		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		1087135 UBP22_HUMAN (744-1109): 3.1e-111: 358: 27.72		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391971 UBP22_HUMAN (744-1109): 3.1e-111: 358: 27.72		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		905382 UBP46_HUMAN (767-1109): 5.5e-107: 341: 27.22		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		1058217 UBP10_HUMAN (388-1110): 2.96e-101: 340: 17.99		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		259285 UBP12_HUMAN (767-1110): 2.83e-106: 339: 27.70		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		1087027 UBP51_HUMAN (728-1110): 1.45e-100: 336: 24.76		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		391756 UBP51_HUMAN (728-1110): 1.45e-100: 336: 24.76		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		1151394 UBP21_HUMAN (605-1111): 9.13e-98: 323: 26.08		H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64
+	Hs
		555516 UBP49_HUMAN (612-1115): 7.52e-92: 311: 20.68		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555508 U17L2_HUMAN (776-1111): 3.18e-93: 310: 26.71		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Sc
		392501 UBP8_YEAST (736-1107): 2.66e-97: 319: 26.08		H2A2_YEAST (16-129): 1.63e-52: 163: 78.95
+	Hs
		1087144 UBP15_HUMAN (964-1106): 1.96e-34: 145: 49.65		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		555362 UBP11_HUMAN (964-1106): 7.58e-34: 143: 44.90		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12