Protein: NR1H4
Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14)

Gene: NR1H4
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q96RI1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

659734

RXRB
Retinoic acid receptor RXR-beta

5

20

High-throughput

0.929

High

1078537

NCOA1
Nuclear receptor coactivator 1

5

20

Small-scale

0.922

High

818885

RXRG
Retinoic acid receptor RXR-gamma

3

20

High-throughput

0.845

High

587194

RXRA
Retinoic acid receptor RXR-alpha

2

20

Small-scale

0.821

High

370250

ESR1
Estrogen receptor

2

19

Small-scale

0.776

High

523950

XRCC6
X-ray repair cross-complementing protein 6

1

15

Small-scale

0.586

High

525024

XRCC5
X-ray repair cross-complementing protein 5

1

15

Small-scale

0.586

High

944378

PRKDC
DNA-dependent protein kinase catalytic subunit

1

12

Small-scale

0.586

High

1259476

SETD7
Histone-lysine N-methyltransferase SETD7

1

5

Small-scale

0.586

High

1300895

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

20

Small-scale

0.561

High

1289401

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

20

Small-scale

0.536

High

1292463

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

20

Small-scale

0.527

High

256426

PHF2
Lysine-specific demethylase PHF2

1

20

Small-scale

0.516

High

935142

H31
Histone H3.1

1

5

Small-scale

0.501

High

998995

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.501

High

1057785

NCOA6
Nuclear receptor coactivator 6

1

20

Small-scale

0.501

High

1059348

CASP8
Caspase-8

1

5

Small-scale

0.501

High

1164506

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

20

Small-scale

0.501

High

1300897

NCOR2
Nuclear receptor corepressor 2

1

20

Small-scale

0.501

High

984281

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

3

Small-scale

0.481

High

131051

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

8

High-throughput

0.479

High

261568

NCOR1
Nuclear receptor corepressor 1

1

20

Small-scale

0.479

High

924802

GRB2
Growth factor receptor-bound protein 2

1

16

High-throughput

0.479

High

928172

SUMO1
Small ubiquitin-related modifier 1

1

11

Small-scale

0.479

High

978858

TF65
Transcription factor p65

1

20

Small-scale

0.479

High

983897

KPCZ
Protein kinase C zeta type

1

17

Small-scale

0.479

High

1016094

SRBP2
Sterol regulatory element-binding protein 2

1

20

Small-scale

0.479

High

1028197

GPS2
G protein pathway suppressor 2

1

4

Small-scale

0.479

High

1204080

CARM1
Histone-arginine methyltransferase CARM1

1

20

Small-scale

0.479

High

1300892

ANM1
Protein arginine N-methyltransferase 1

1

20

Small-scale

0.479

High

1300893

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

2

Small-scale

0.479

High

1300894

MLXPL
Carbohydrate-responsive element-binding protein

1

20

Small-scale

0.479

High

1300896

HDAC6
Histone deacetylase 6

1

20

Small-scale

0.479

High

1060149

ARI5B
AT-rich interactive domain-containing protein 5B

1

20

Small-scale

0.445

High

382113

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.439

High

679631

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024