Interactor 1: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28515276
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~eIF2_C, GTP_EFTU_D2~eIF2_C, EFG_C~GTP_EFTU, EFG_III~GTP_EFTU, EFG_IV~GTP_EFTU, EFTUD2~GTP_EFTU, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, EFG_III~GTP_EFTU_D2, EFTUD2~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 472
Hs

1 972
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Ec
+ Ec
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024