Protein: GUAA
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)

Gene: GUAA, GUA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P38625

Gene Ontology (top 5):
GO:0003921 - GMP synthase activity
GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006177 - GMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366218

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.584

High

751194

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

511155

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.571

High

751193

SSB2
Ribosome-associated molecular chaperone SSB2

2

13

High-throughput

0.552

High

751199

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

697318

GLRX4
Monothiol glutaredoxin-4

1

2

Small-scale

0.481

High

751203

GLRX3
Monothiol glutaredoxin-3

1

2

Small-scale

0.481

High

407015

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

407883

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

425921

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

480640

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

485717

IF4A
ATP-dependent RNA helicase eIF4A

1

4

High-throughput

0.479

High

543661

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

605993

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

627994

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

631845

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

680666

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

700870

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

703602

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

751190

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

751191

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

751195

MPS3
Spindle pole body assembly component MPS3

1

2

High-throughput

0.479

High

751196

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

751200

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

751202

GIS1
Transcriptional activator/repressor GIS1

1

1

High-throughput

0.479

High

751204

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

751207

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

491083

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

751201

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.445

High

524277

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.437

High

662106

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

688216

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

745632

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

751189

RPN1
26S proteasome regulatory subunit RPN1

1

4

High-throughput

0.437

High

751192

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

751198

HST2
NAD-dependent protein deacetylase HST2

1

6

High-throughput

0.437

High

751205

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

751208

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

425336

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

431363

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.279

Low

751197

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

751206

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

751209

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024