Interactor 1: LEP (P41160)
Leptin (Obesity factor)
Gene: LEP

Interactor 2: LEPR (P48356)
Leptin receptor (LEP-R) (B219) (OB receptor) (OB-R) (CD antigen CD295)
Gene: LEPR

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.575

The method score is based on:

Property Details
Experiments 24882746
Identification Methods x ray scattering, field flow fractionation, static light scattering, isothermal titration calorimetry, transmission electron microscopy, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005615 - extracellular space
GO:0006909 - phagocytosis
GO:0008203 - cholesterol metabolic process
GO:0010507 - negative regulation of autophagy
and 10 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 167
Mm

1 1162
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024