Interactor 1: HEL1 (P36113)
E3 ubiquitin-protein ligase HEL1 (EC 2.3.2.31) (Histone E3 ligase 1) (RING-type E3 ubiquitin transferase HEL1)
Gene: HEL1

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 39437715
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ariadne~Cullin, Cullin_Nedd8~IBR, Cullin~IBR_1
Common GO terms GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 551
Sc

1 815
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Last updated: 11Aug2025