HitPredict

Interactor 1: PERI (P41219)
Peripherin (Neurofilament 4)
Gene: PRPH

Interactor 2: NEST (P48681)
Nestin
Gene: NES

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005737 - cytoplasm GO:0005882 - intermediate filament
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 470 Hs			1 1621
+	Hs
		409022 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68
+	Hs
		443379 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		VIME_HUMAN (8-343): 3.05e-118: 382: 28.32
+	Hs
		443391 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		NEST_HUMAN (1-1621): 1.09e-115: 404: 100.00
+	Hs
		408979 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68
+	Hs
		443278 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		VIME_HUMAN (8-343): 3.05e-118: 382: 28.32
+	Hs
		318786 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		K2C75_HUMAN (6-319): 4.7e-60: 219: 21.43
+	Hs
		318768 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		K2C75_HUMAN (6-319): 4.7e-60: 219: 21.43
+	Hs
		318775 DESM_HUMAN (56-462): 7.2e-129: 383: 62.26		K2C75_HUMAN (6-319): 4.7e-60: 219: 21.43
+	Hs
		535339 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35
+	Hs
		166107 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		SYNEM_HUMAN (6-311): 3.29e-17: 90.5: 33.97
+	Hs
		781902 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		AINX_HUMAN (8-317): 2.29e-17: 89.4: 27.59
+	Hs
		569056 PERI_HUMAN (1-470): 2.22e-164: 474: 100.00		DESM_HUMAN (8-316): 2.1e-14: 79.7: 25.47
+	Hs
		443295 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35
+	Hs
		422126 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95
+	Hs
		166095 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		SYNEM_HUMAN (6-311): 3.29e-17: 90.5: 33.97
+	Hs
		443539 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		AINX_HUMAN (8-317): 2.29e-17: 89.4: 27.59
+	Hs
		422326 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		NFM_HUMAN (8-333): 4.76e-14: 79.7: 26.21
+	Hs
		443316 VIME_HUMAN (10-458): 2.68e-145: 425: 56.79		DESM_HUMAN (8-316): 2.1e-14: 79.7: 25.47
+	Hs
		166100 DESM_HUMAN (56-462): 7.2e-129: 383: 62.26		SYNEM_HUMAN (6-311): 3.29e-17: 90.5: 33.97