HitPredict

Interactor 1: IPP2 (P41236)
Protein phosphatase inhibitor 2 (IPP-2)
Gene: PPP1R2

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.983

Property	Details
Experiments	26186194, 27880917, 28514442, 27173435, 28330616, 29669786, 33961781, 22321011, 20826336, 25593058, 10807923
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, nuclear magnetic resonance, x ray scattering, molecular sieving, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation and 1 others more... filter binding
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	GO:0005977 - glycogen metabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 330
+	Hs
		905971 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Mm
		906370 IPP2_MOUSE (1-205): 6.71e-75: 226: 83.98		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		737628 IPP2_HUMAN (1-205): 2.8e-78: 234: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		737869 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		782715 IPP2_HUMAN (1-205): 2.8e-78: 234: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		906500 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		164068 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		164067 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		164069 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Dm
		65575 A8JNP7_DROME (1-161): 9.78e-47: 157: 39.13		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		65574 A8JNP7_DROME (1-161): 9.78e-47: 157: 39.13		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		65576 A8JNP7_DROME (1-161): 9.78e-47: 157: 39.13		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		65577 A8JNP7_DROME (1-161): 9.78e-47: 157: 39.13		PP13_DROME (5-304): 0: 550: 91.67
+	Dm
		819222 Q9V3C7_DROME (1-161): 4.81e-39: 134: 39.13		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		524615 Q4V424_DROME (40-198): 3.77e-44: 150: 19.02		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		819260 Q4V424_DROME (40-198): 3.77e-44: 150: 19.02		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		1118462 Q4V424_DROME (40-198): 3.77e-44: 150: 19.02		Q8T0U6_DROME (19-326): 0: 537: 84.42
+	Dm
		524639 Q9V3C7_DROME (1-161): 4.81e-39: 134: 39.13		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		819290 Q9V3C7_DROME (1-161): 4.81e-39: 134: 39.13		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		984191 Q9V3C7_DROME (1-161): 4.81e-39: 134: 39.13		PP13_DROME (5-304): 0: 550: 91.67