HitPredict

Interactor 1: SYIC (P41252)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
Gene: IARS1

Interactor 2: AIMP2 (Q13155)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)
Gene: AIMP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.687

The method score is based on:

Property Details
Experiments 33961781, 31792442, 9878398, 35546148
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0016020 - membrane
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1262
Hs

1 320
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024