Interactor 1: EZ (P42124)
Histone-lysine N-methyltransferase E(z) (EC 2.1.1.356) (Lysine N-methyltransferase 6) (Protein enhancer of zeste)
Gene: E(z)
Interactor 2: SUZ12 (Q9NJG9)
Polycomb protein Su(z)12 (Suppressor 12 of zeste protein)
Gene: Su(z)12
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12697833, 15776017, 22493065, 12408864, 26063573, 24100017, 29242288, 19767730, 25242320, 18276122 |
| Identification Methods | affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRC2_HTH_1~VEFS-Box, VEFS-Box~preSET_CXC, SET~VEFS-Box |
| Common GO terms | GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0022008 - neurogenesis GO:0035097 - histone methyltransferase complex and 3 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
