HitPredict

Interactor 1: STAT6 (P42226)
Signal transducer and activator of transcription 6 (IL-4 Stat)
Gene: STAT6

Interactor 2: STAT6 (P42226)
Signal transducer and activator of transcription 6 (IL-4 Stat)
Gene: STAT6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 22000020
Identification Methods anti tag coimmunoprecipitation, comigration in non denaturing gel electrophoresis
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 28 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 847
Hs

1 847
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Last updated: 15 Jul 2024