HitPredict - High confidence protein-protein interactions

Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: FOXP3 (Q99JB6)
Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form]
Gene: FOXP3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	22922362, 19797626
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus and 14 others more... GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0006366 - transcription by RNA polymerase II GO:0006954 - inflammatory response GO:0008285 - negative regulation of cell population proliferation GO:0010467 - gene expression GO:0010628 - positive regulation of gene expression GO:0042803 - protein homodimerization activity GO:0043565 - sequence-specific DNA binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050728 - negative regulation of inflammatory response
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	770
Mm

1	429

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024