HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PPR18 (Q6NYC8)
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)
Gene: PPP1R18

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26186194, 27880917, 28514442, 30344098, 33961781, 23080069, 21382349, unassigned3799, 24366813
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 613
+	Hs
		967805 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR18_HUMAN (1-613): 8.37e-74: 249: 100.00
+	Hs
		968346 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR18_HUMAN (1-613): 8.37e-74: 249: 100.00
+	Mm
		968147 PP1A_MOUSE (1-323): 0: 579: 90.36		PPR18_MOUSE (1-613): 2.34e-55: 199: 73.54
+	Hs
		786641 PP1G_HUMAN (1-323): 0: 603: 100.00		TPRN_HUMAN (206-554): 4.5e-28: 121: 19.95
+	Hs
		967775 PP1A_HUMAN (1-323): 0: 579: 90.66		TPRN_HUMAN (206-554): 4.5e-28: 121: 19.95
+	Hs
		968325 PP1B_HUMAN (1-322): 0: 560: 86.89		TPRN_HUMAN (206-554): 4.5e-28: 121: 19.95
+	Hs
		967727 PP1A_HUMAN (1-323): 0: 579: 90.66		MDC1_HUMAN (15-599): 3.34e-18: 91.2: 8.86
+	Hs
		967847 PP1A_HUMAN (1-323): 0: 579: 90.66		Q8IZ53_HUMAN (322-554): 4.21e-16: 82.6: 23.64
+	Ce
		876756 GLC7B_CAEEL (3-323): 0: 584: 89.63		MEL28_CAEEL (92-585): 1.1e-12: 73.7: 13.52
+	Dm
		119664 PP1B_DROME (1-323): 0: 552: 82.48		M9PB30_DROME (148-580): 4.47e-13: 75.1: 11.94
+	Ce
		1166060 GLC7A_CAEEL (1-323): 0: 549: 83.28		MEL28_CAEEL (92-585): 1.1e-12: 73.7: 13.52
+	Dm
		55696 Q8T0U6_DROME (19-323): 0: 535: 83.39		A1Z9J3_DROME (203-609): 5.93e-12: 71.2: 10.12
+	Hs
		994221 PP2AA_HUMAN (8-312): 5.37e-178: 496: 46.08		MDC1_HUMAN (15-599): 3.34e-18: 91.2: 8.86