Interactor 1: GRIA1 (P42261)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)
Gene: GRIA1

Interactor 2: GRIA2 (P42262)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 10358037, 24706758, 14602821, 18311135
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001540 - amyloid-beta binding
GO:0004971 - AMPA glutamate receptor activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 12 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 906
Hs

1 883
+ Rn
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Rn
+ Rn
+ Mm
+ Mm
+ Mm
+ Rn
+ Hs
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+ Mm
+ Mm

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Last updated: 15 Jul 2024