HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: RASF8 (Q8NHQ8)
Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)
Gene: RASSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.50	0.654

Property	Details
Experiments	24366813, 26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 419
+	Hs
		967860 PP1A_HUMAN (1-323): 0: 579: 90.66		RASF8_HUMAN (1-419): 1.02e-146: 425: 100.00
+	Hs
		296876 PP1G_HUMAN (1-323): 0: 603: 100.00		RASF9_HUMAN (2-411): 1.96e-135: 397: 19.48
+	Hs
		968385 PP1B_HUMAN (1-322): 0: 560: 86.89		RASF8_HUMAN (1-419): 1.02e-146: 425: 100.00
+	Hs
		296878 PP1A_HUMAN (1-323): 0: 579: 90.66		RASF9_HUMAN (2-411): 1.96e-135: 397: 19.48
+	Hs
		296879 PP1B_HUMAN (1-322): 0: 560: 86.89		RASF9_HUMAN (2-411): 1.96e-135: 397: 19.48
+	Hs
		66488 PP1A_HUMAN (1-323): 0: 579: 90.66		RASFA_HUMAN (2-410): 3.8e-114: 345: 14.40
+	Hs
		786552 PP1G_HUMAN (1-323): 0: 603: 100.00		RASF7_HUMAN (1-405): 5.8e-89: 276: 33.66
+	Hs
		967675 PP1A_HUMAN (1-323): 0: 579: 90.66		RASF7_HUMAN (1-405): 5.8e-89: 276: 33.66
+	Hs
		968260 PP1B_HUMAN (1-322): 0: 560: 86.89		RASF7_HUMAN (1-405): 5.8e-89: 276: 33.66
+	Dm
		873538 PP11_DROME (5-323): 0: 569: 88.92		Q9VBP2_DROME (1-81): 1.06e-31: 128: 69.14