HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: RASF7 (Q02833)
Ras association domain-containing protein 7 (HRAS1-related cluster protein 1)
Gene: RASSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 373
+	Hs
		967675 PP1A_HUMAN (1-326): 0: 576: 88.79		RASF7_HUMAN (1-373): 7.3e-135: 391: 100.00
+	Hs
		786552 PP1G_HUMAN (1-327): 0: 569: 86.89		RASF7_HUMAN (1-373): 7.3e-135: 391: 100.00
+	Hs
		296879 PP1B_HUMAN (1-327): 0: 597: 100.00		RASF9_HUMAN (9-317): 2.11e-112: 336: 17.69
+	Hs
		296878 PP1A_HUMAN (1-326): 0: 576: 88.79		RASF9_HUMAN (9-317): 2.11e-112: 336: 17.69
+	Hs
		296876 PP1G_HUMAN (1-327): 0: 569: 86.89		RASF9_HUMAN (9-317): 2.11e-112: 336: 17.69
+	Hs
		968409 PP1B_HUMAN (1-327): 0: 597: 100.00		ASPP1_HUMAN (5-340): 7.74e-84: 277: 15.33
+	Mm
		968117 PP1A_MOUSE (1-326): 0: 576: 88.49		ASPP1_MOUSE (5-340): 9.4e-89: 290: 16.88
+	Hs
		968385 PP1B_HUMAN (1-327): 0: 597: 100.00		RASF8_HUMAN (8-308): 3.86e-85: 266: 35.41
+	Hs
		967916 PP1A_HUMAN (1-326): 0: 576: 88.79		ASPP1_HUMAN (5-340): 7.74e-84: 277: 15.33
+	Hs
		786785 PP1G_HUMAN (1-327): 0: 569: 86.89		ASPP1_HUMAN (5-340): 7.74e-84: 277: 15.33
+	Hs
		967860 PP1A_HUMAN (1-326): 0: 576: 88.79		RASF8_HUMAN (8-308): 3.86e-85: 266: 35.41
+	Hs
		786738 PP1G_HUMAN (1-327): 0: 569: 86.89		RASF8_HUMAN (8-308): 3.86e-85: 266: 35.41
+	Hs
		66488 PP1A_HUMAN (1-326): 0: 576: 88.79		RASFA_HUMAN (9-313): 8.74e-79: 252: 15.10
+	Hs
		968289 PP1B_HUMAN (1-327): 0: 597: 100.00		ASPP2_HUMAN (5-353): 5.08e-39: 150: 14.21
+	Mm
		98307 PP1A_MOUSE (1-326): 0: 576: 88.49		E9QJU8_MOUSE (5-365): 2.57e-39: 151: 15.31
+	Hs
		967717 PP1A_HUMAN (1-326): 0: 576: 88.79		ASPP2_HUMAN (5-353): 5.08e-39: 150: 14.21
+	Hs
		786595 PP1G_HUMAN (1-327): 0: 569: 86.89		ASPP2_HUMAN (5-353): 5.08e-39: 150: 14.21
+	Dm
		873538 PP11_DROME (6-327): 0: 567: 85.09		Q9VBP2_DROME (8-88): 4.71e-30: 122: 56.79