Interactor 1: PK3CB (P42338)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1)
Gene: PIK3CB

Interactor 2: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11432782
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~Ras, PI3K_rbd~Ras
Common GO terms GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1070
Hs

1 215
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024