HitPredict

Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.653

The method score is based on:

Property Details
Experiments 20080789, 26593251
Identification Methods affinity chromatography technology, enzymatic study, protein kinase assay, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0007281 - germ cell development
GO:0010507 - negative regulation of autophagy
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2549
Hs

1 233
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024