Protein: EST3
Carboxylesterase 3 (EC 3.1.1.1) (Liver carboxylesterase 31 homolog)

Gene: EST3, CES3
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q6UWW8

Gene Ontology (top 5):
GO:0005788 - endoplasmic reticulum lumen
GO:0005829 - cytosol
GO:0006805 - xenobiotic metabolic process
GO:0034383 - low-density lipoprotein particle clearance
GO:0052689 - carboxylic ester hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144614

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

4

High-throughput

0.770

High

593403

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.691

High

731863

CEAM8
Cell adhesion molecule CEACAM8

1

5

High-throughput

0.691

High

422381

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.628

High

388644

C1QA
Complement C1q subcomponent subunit A

1

3

High-throughput

0.489

High

2105

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.481

High

717509

PDIA3
Protein disulfide-isomerase A3

1

4

High-throughput

0.479

High

430054

JUN
Transcription factor Jun

1

4

High-throughput

0.437

High

1118372

BMPR2
Bone morphogenetic protein receptor type-2

1

2

Small-scale

0.437

High

1248896

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

907152

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.328

High

1212713

TMTC4
Protein O-mannosyl-transferase TMTC4

2

0

High-throughput

0.324

High

1248897

D106A
Beta-defensin 106

1

0

High-throughput

0.279

Low

1248898

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.279

Low

1248899

SPXN
Spexin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025