HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: LMTK3 (Q96Q04)
Serine/threonine-protein kinase LMTK3 (EC 2.7.11.1) (Lemur tyrosine kinase 3)
Gene: LMTK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35044719
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 896 Hs			1 1460
+	Hs
		787931 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		LMTK1_HUMAN (14-1439): 0: 685: 30.30
+	Hs
		1300028 ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40		LMTK3_HUMAN (1-1460): 0: 925: 100.00
+	Hs
		337383 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		ABL1_HUMAN (65-993): 2.2e-127: 426: 17.10
+	Hs
		1168427 ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40		LMTK1_HUMAN (14-1439): 0: 685: 30.30
+	Hs
		1078847 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		LMTK1_HUMAN (14-1439): 0: 685: 30.30
+	Hs
		384432 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		601605 ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40		FGFR2_HUMAN (2-471): 1.02e-125: 413: 21.64
+	Hs
		508233 ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40		FGFR1_HUMAN (2-458): 1.89e-124: 410: 23.51
+	Hs
		1132678 FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35		TNIK_HUMAN (113-1160): 1.11e-136: 457: 12.41
+	Hs
		508022 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		FGFR1_HUMAN (2-458): 1.89e-124: 410: 23.51
+	Hs
		665608 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		EPHB2_HUMAN (6-461): 2.86e-120: 405: 21.46
+	Hs
		411908 MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72		LCK_HUMAN (70-423): 2.76e-111: 363: 24.66
+	Hs
		434101 MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72		LYN_HUMAN (79-423): 6.29e-109: 357: 23.71
+	Ce
		371330 Q9BIF4_CAEEL (7-213): 5.25e-19: 94.5: 37.55		ABL1_CAEEL (30-974): 1.41e-126: 426: 15.16
+	Hs
		433781 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		LYN_HUMAN (79-423): 6.29e-109: 357: 23.71
+	Ce
		106690 Q9BIF4_CAEEL (7-213): 5.25e-19: 94.5: 37.55		SRC1_CAEEL (63-421): 4.96e-107: 352: 25.13
+	Hs
		385802 MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		435760 EHD1_HUMAN (17-102): 8.74e-16: 83.5: 33.72		IGF1R_HUMAN (128-400): 3.54e-40: 165: 35.74
+	Rn
		621629 EHD1_RAT (17-102): 8.82e-16: 83.5: 32.56		IGF1R_RAT (128-400): 1.53e-38: 159: 35.38
+	Hs
		385521 EHD1_HUMAN (17-102): 8.74e-16: 83.5: 33.72		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88