HitPredict

Interactor 1: AF9 (P42568)
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
Gene: MLLT3

Interactor 2: ELL (P55199)
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)
Gene: ELL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	32152128, 36036574, 20431927, 20854876, 21729782
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008023 - transcription elongation factor complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 621
+	Hs
		130146 AF9_HUMAN (1-568): 1.02e-96: 307: 100.00		ELL2_HUMAN (2-620): 0: 772: 45.76
+	Hs
		876636 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		ELL_HUMAN (1-621): 0: 833: 100.00
+	Hs
		130155 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		ELL2_HUMAN (2-620): 0: 772: 45.76
+	Hs
		788066 AF9_HUMAN (1-568): 1.02e-96: 307: 100.00		ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53
+	Hs
		297831 K0754_HUMAN (160-531): 5.43e-39: 155: 12.30		OCLN_HUMAN (358-616): 8.61e-79: 260: 25.57
+	Hs
		1084127 US6NL_HUMAN (188-529): 2.46e-37: 149: 13.09		OCLN_HUMAN (358-616): 8.61e-79: 260: 25.57
+	Hs
		974520 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53
+	Hs
		965110 ANK2_HUMAN (186-504): 6.94e-10: 64.4: 11.15		OCLN_HUMAN (358-616): 8.61e-79: 260: 25.57
+	Dm
		1365313 Q9VF92_DROME (5-506): 6.98e-37: 148: 23.48		ELL_DROME (479-619): 3.66e-34: 141: 33.10
+	Dm
		2367 A0A0B4KG69_DROME (5-506): 7.02e-37: 148: 23.48		ELL_DROME (479-619): 3.66e-34: 141: 33.10