HitPredict

Interactor 1: HPCL1 (P37235)
Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3)
Gene: HPCAL1

Interactor 2: HPCA (P84074)
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)
Gene: HPCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	35575683, 33961781, 31839598
Identification Methods	cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_1~EF-hand_7, EF-hand_7~EF-hand_7
Common GO terms	GO:0005509 - calcium ion binding GO:0009966 - regulation of signal transduction GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 193
+	Hs
		789624 HPCL1_HUMAN (1-193): 1.44e-60: 188: 100.00		NCALD_HUMAN (1-193): 3.56e-58: 182: 88.08
+	Hs
		962890 NCALD_HUMAN (1-193): 1.66e-58: 183: 90.67		HPCA_HUMAN (1-193): 1.45e-57: 181: 100.00
+	Hs
		962888 NCALD_HUMAN (1-193): 1.66e-58: 183: 90.67		VISL1_HUMAN (1-189): 9.66e-49: 158: 65.97
+	Hs
		1449090 KCIP1_HUMAN (9-188): 7.74e-52: 167: 43.33		KCIP2_HUMAN (8-188): 3.63e-48: 159: 43.09
+	Hs
		1244863 KCIP1_HUMAN (9-188): 7.74e-52: 167: 43.33		KCIP4_HUMAN (3-188): 2.2e-45: 152: 39.25
+	Hs
		1449089 KCIP2_HUMAN (4-188): 3.71e-48: 159: 40.54		KCIP2_HUMAN (8-188): 3.63e-48: 159: 43.09
+	Gm
		1284629 Q84P28_SOYBN (3-185): 2.49e-46: 160: 23.78		Q84P28_SOYBN (3-178): 3.3e-44: 154: 22.03
+	At
		1182290 CDPK4_ARATH (3-185): 5.82e-46: 159: 23.91		CDPK4_ARATH (3-179): 1.16e-43: 153: 23.03
+	Hs
		1244862 KCIP2_HUMAN (4-188): 3.71e-48: 159: 40.54		KCIP4_HUMAN (3-188): 2.2e-45: 152: 39.25
+	Hs
		968626 NCS1_HUMAN (1-187): 3.58e-47: 154: 59.89		NCS1_HUMAN (1-187): 3.46e-47: 154: 58.82