HitPredict

Interactor 1: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1

Interactor 2: IL23R (Q5VWK5)
Interleukin-23 receptor (IL-23 receptor) (IL-23R)
Gene: IL23R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 12023369
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002230 - positive regulation of defense response to virus by host
GO:0002827 - positive regulation of T-helper 1 type immune response
GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane
and 11 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 662
Hs

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Last updated: 15 Jul 2024