Protein: HPCA
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)

Gene: HPCA
Organism: Homo sapiens
Interactions: 40
UniProt ID: P84074

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009966 - regulation of signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

789630

HPCL1
Hippocalcin-like protein 1

3

10

High-throughput

0.847

High

962890

NCALD
Neurocalcin-delta

3

9

High-throughput

0.847

High

1009756

M3K9
Mitogen-activated protein kinase kinase kinase 9

2

12

High-throughput

0.789

High

1014864

ABHD6
Monoacylglycerol lipase ABHD6

1

1

High-throughput

0.691

High

1014855

DGUOK
Deoxyguanosine kinase, mitochondrial

3

4

High-throughput

0.667

High

1014868

KTU
Protein kintoun

3

3

High-throughput

0.667

High

1014859

DTX2
Probable E3 ubiquitin-protein ligase DTX2

3

6

High-throughput

0.665

High

64631

AN33B
Ankyrin repeat domain-containing protein 33B

1

3

High-throughput

0.618

High

1014850

M3K10
Mitogen-activated protein kinase kinase kinase 10

2

13

Small-scale

0.611

High

1014857

M3K21
Mitogen-activated protein kinase kinase kinase 21

2

12

High-throughput

0.611

High

124305

HAX1
HCLS1-associated protein X-1

3

3

High-throughput

0.609

High

1014871

NUFP1
FMR1-interacting protein NUFIP1

3

4

High-throughput

0.609

High

1014851

CREM
cAMP-responsive element modulator

2

5

High-throughput

0.606

High

1014856

VWC2
Brorin

2

1

High-throughput

0.606

High

190213

MOT4
Monocarboxylate transporter 4

2

0

High-throughput

0.580

High

1014863

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

1014870

I36RA
Interleukin-36 receptor antagonist protein

2

0

High-throughput

0.580

High

936507

AF10
Protein AF-10

2

1

High-throughput

0.553

High

1014862

MYDGF
Myeloid-derived growth factor

2

2

High-throughput

0.553

High

1014865

GATA5
Transcription factor GATA-5

2

1

High-throughput

0.553

High

1014866

C1QT2
Complement C1q tumor necrosis factor-related protein 2

2

7

High-throughput

0.553

High

251446

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

3

High-throughput

0.536

High

709113

TPP2
Tripeptidyl-peptidase 2

1

2

High-throughput

0.536

High

719613

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

3

High-throughput

0.536

High

906870

GPM6A
Neuronal membrane glycoprotein M6-a

1

4

High-throughput

0.536

High

370037

CYTC
Cystatin-C

1

0

High-throughput

0.513

High

1014852

BIRC1
Baculoviral IAP repeat-containing protein 1

1

0

Small-scale

0.480

High

1014854

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

12

High-throughput

0.479

High

1014869

IRAK4
Interleukin-1 receptor-associated kinase 4

1

1

High-throughput

0.479

High

988947

AP2B1
AP-2 complex subunit beta

1

0

Small-scale

0.460

High

390536

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.458

High

413619

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

1014853

GRM2
Metabotropic glutamate receptor 2

1

0

Small-scale

0.458

High

1014860

TRXR3
Thioredoxin reductase 3

1

1

High-throughput

0.445

High

1014867

TX101
Testis-expressed protein 101

1

2

High-throughput

0.407

High

506717

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

553806

KCRU
Creatine kinase U-type, mitochondrial

2

0

High-throughput

0.316

High

577957

QCR7
Cytochrome b-c1 complex subunit 7

2

0

High-throughput

0.316

High

1014858

DHDDS
Dehydrodolichyl diphosphate synthase complex subunit DHDDS

1

0

High-throughput

0.279

Low

1014861

PUSL1
tRNA pseudouridine synthase-like 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025