HitPredict

Interactor 1: LPPRC (P42704)
Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130)
Gene: LRPPRC

Interactor 2: DUS6 (Q16828)
Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
Gene: DUSP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	28675297, 31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1394 Hs			1 381
+	Hs
		789759 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS2_HUMAN (11-347): 6.86e-102: 305: 33.43
+	Hs
		659257 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS1_HUMAN (23-373): 1.17e-99: 302: 32.77
+	Hs
		789770 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS4_HUMAN (29-374): 6.65e-96: 293: 33.05
+	Hs
		304930 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS14_HUMAN (206-359): 7.93e-59: 191: 32.47
+	Hs
		789892 LPPRC_HUMAN (1-1394): 0: 860: 100.00		STYX_HUMAN (187-375): 1.18e-58: 191: 26.80
+	Hs
		789821 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS28_HUMAN (200-362): 2.03e-55: 181: 27.61
+	Hs
		789959 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS26_HUMAN (204-349): 1.57e-53: 178: 30.67
+	Hs
		789995 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS21_HUMAN (199-355): 5.14e-53: 176: 25.48
+	Hs
		789719 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS3_HUMAN (194-354): 5.11e-53: 175: 31.36
+	Hs
		789986 LPPRC_HUMAN (1-1394): 0: 860: 100.00		DUS15_HUMAN (210-343): 7.3e-15: 76.3: 36.03