HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: VDAC2 (P45880)
Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2)
Gene: VDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	32814053, 17500595
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 294
+	Hs
		601164 HD_HUMAN (1-3142): 0: 5724: 100.00		VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56
+	Hs
		792105 HD_HUMAN (1-3142): 0: 5724: 100.00		VDAC3_HUMAN (12-294): 1.21e-108: 318: 73.50
+	Mm
		103027 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		VDAC2_MOUSE (8-294): 2.24e-123: 355: 96.86
+	Mm
		103029 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		VDAC1_MOUSE (12-294): 1.63e-111: 325: 74.21
+	Mm
		103028 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		VDAC3_MOUSE (12-294): 1.5e-108: 318: 73.85