HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: STXB1 (P61764)
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.588

The method score is based on:

Property Details
Experiments 32814053, 17500595
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030424 - axon
GO:0032991 - protein-containing complex
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 594
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024