Protein: SRGP3
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)

Gene: SRGP3, SRGAP3
Organism: Homo sapiens
Interactions: 55
UniProt ID: O43295

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0030336 - negative regulation of cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

212750

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

3

15

High-throughput

0.861

High

212770

ASPP2
Apoptosis-stimulating of p53 protein 2

3

7

High-throughput

0.861

High

212780

ASPP1
Apoptosis-stimulating of p53 protein 1

3

8

High-throughput

0.861

High

212777

RHG24
Rho GTPase-activating protein 24

2

15

High-throughput

0.767

High

212776

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

2

4

High-throughput

0.737

High

212764

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.724

High

192890

CLOCK
Circadian locomoter output cycles protein kaput

3

2

High-throughput

0.667

High

212782

SPAG5
Sperm-associated antigen 5

3

12

High-throughput

0.667

High

212765

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

212744

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

14

Small-scale

0.618

High

212785

SH3G1
Endophilin-A2

1

17

Small-scale

0.618

High

212786

SH3G2
Endophilin-A1

1

17

Small-scale

0.618

High

66561

CC85C
Coiled-coil domain-containing protein 85C

3

2

High-throughput

0.609

High

212791

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

212790

TNIK
TRAF2 and NCK-interacting protein kinase

2

8

High-throughput

0.590

High

212788

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.576

High

212754

NKTR
NK-tumor recognition protein

2

5

High-throughput

0.571

High

212793

ROBO1
Roundabout homolog 1

2

4

High-throughput

0.571

High

212753

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.536

High

212766

VAMP2
Vesicle-associated membrane protein 2

1

1

High-throughput

0.536

High

212767

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

212771

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.536

High

212773

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.536

High

212784

KIF2C
Kinesin-like protein KIF2C

1

5

High-throughput

0.536

High

212789

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.536

High

212762

S10AA
Protein S100-A10

1

9

High-throughput

0.515

High

212783

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.513

High

212758

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

3

Small-scale

0.501

High

212792

MAN1
Inner nuclear membrane protein Man1

1

3

High-throughput

0.489

High

212749

CCD22
Coiled-coil domain-containing protein 22

1

2

High-throughput

0.479

High

212756

SYUA
Alpha-synuclein

1

4

High-throughput

0.479

High

212769

CUL3
Cullin-3

1

9

High-throughput

0.479

High

212772

EEA1
Early endosome antigen 1

1

7

High-throughput

0.479

High

212774

RN123
E3 ubiquitin-protein ligase RNF123

1

8

High-throughput

0.479

High

212775

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

212752

H12
Histone H1.2

1

6

High-throughput

0.470

High

212746

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.464

High

212781

ANM6
Protein arginine N-methyltransferase 6

1

3

High-throughput

0.464

High

212778

DTBP1
Dysbindin

1

0

High-throughput

0.460

High

212763

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

212779

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

212757

HD
Huntingtin

1

6

High-throughput

0.457

High

212768

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.457

High

212755

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.445

High

212761

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

212787

ENKD1
Enkurin domain-containing protein 1

1

2

High-throughput

0.439

High

104881

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

212747

NDK8
Putative nucleoside diphosphate kinase

1

3

High-throughput

0.407

High

212759

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

5

Small-scale

0.407

High

212760

PGTB1
Geranylgeranyl transferase type-1 subunit beta

3

0

High-throughput

0.347

High

65657

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.279

Low

212751

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

212745

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

212748

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025